Methyl Triphenyl Phosphonium Chloride
Pharmaceutical Materials 2025-03-02
CAS Number: 1031-15-8
Molecular Formula: C19H18ClP
Molecular Weight: 312.77 g/mol
Appearance: White powder or crystals Melting Point: 221°C (dec.)
Usage: It is used as a pharmaceutical intermediate.
| Attribute | Details |
|---|---|
| Chemical Name | Methyl Triphenyl Phosphonium Chloride |
| Synonyms | Triphenylmethylchlorophosphine; Methyltriphenylphosphonium Chloride; Chloro(methyl)triphenyl-λ5-phosphane |
| CAS Number | 1031-15-8 (also listed as 1013-15-8 in some sources) |
| Molecular Formula | C19H18ClP |
| Molecular Weight | 312.773 g/mol |
| Appearance | White crystalline solid |
| Melting Point | 221°C (decomposition) |
| Solubility | Soluble in organic solvents |
| Chemical Structure | A quaternary phosphonium salt with a methyl group attached to the phosphorus atom, and three phenyl groups attached to the phosphorus atom via covalent bonds. The chloride ion is the counterion. |
| Physical Properties | Odorless or with a faint odor. Stable under normal conditions. |
| Chemical Properties | Methyl Triphenyl Phosphonium Chloride exhibits typical phosphonium salt reactivity. It can be used as a reagent in organic synthesis, particularly in Wittig reactions and related phosphorus-based transformations. |
| Applications | Used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. It is also employed in research settings for the preparation of complex organic molecules. |
| Safety Information | Handle with caution. Avoid contact with skin, eyes, and clothing. Wear appropriate protective clothing, gloves, and eye protection. Store in a cool, dry place away from incompatible materials and oxidizing agents. Follow local regulations for the safe handling and disposal of chemicals. |
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