Methyl 4-iodobenzoate

Pharmaceutical Materials 2025-03-03

CAS Number: 619-44-3

Molecular Formula: C8H7IO2

Molecular Weight: 262.04 g/mol

Appearance: Beige to pale pink crystalline powder

Melting Point: 112-116°C

Boiling Point: 278.5°C (estimated)

Density: 2.02 g/cm³

Usage: Used as an organic intermediate in chemical synthesis.

 

Aspect Details
Name Methyl 4-Iodobenzoate
CAS No. 619-59-2
Molecular Formula C₈H₇IO₂
Molecular Weight 262.05 g/mol
Physical Properties
  • Appearance: White to off-white crystalline solid
  • Melting Point: 84-86 °C
  • Density: 1.87 g/cm³ (calculated)
  • Solubility: Insoluble in water; soluble in organic solvents such as ethanol, DMSO, and dichloromethane
Chemical Properties Contains an iodine atom attached to the aromatic ring, making it a versatile intermediate in organic synthesis. It can undergo nucleophilic substitution, cross-coupling reactions (e.g., Suzuki-Miyaura, Stille coupling), and metal-catalyzed transformations.
Applications
  • Used in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals
  • As a key intermediate in the preparation of bioactive compounds and fluorescent probes
  • Employed in material science for the development of functional polymers and liquid crystals
Safety Information
  • Handle with caution due to potential irritation to skin, eyes, and respiratory tract
  • Store in a cool, dry place away from light and moisture

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