Methyl 4-amino-2-chlorobenzoate
Pharmaceutical Materials 2025-03-02
CAS Number: 46004-37-9
Molecular Formula: C8H8ClNO2
Molecular Weight: 185.61 g/mol
Appearance: White powder or crystalline solid
Usage: It is mainly used as an intermediate in the production of pharmaceuticals and other chemicals.
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| Category | Details |
|---|---|
| Chemical Name | Methyl 4-amino-2-chlorobenzoate |
| CAS Number | 554-10-1 |
| Molecular Formula | C8H8ClNO2 |
| Molecular Weight | 185.61 g/mol |
| Chemical Structure | Aromatic ring with a methoxy group at the meta position, an amino group at the para position, and a chloro group at the ortho position. |
| Appearance | Colorless to pale yellow crystalline solid |
| Melting Point | 145-147°C |
| Boiling Point | Not applicable (decomposes before boiling) |
| Solubility | Soluble in organic solvents such as ethanol, ether, and acetone; slightly soluble in water. |
| Chemical Properties | Aromatic amine with potential to undergo various reactions such as acetylation, alkylation, and diazotization. |
| Applications | Used as an intermediate in the synthesis of dyes, pigments, and pharmaceuticals. Has potential applications in the development of new materials and functional polymers. |
| Synthesis Methods | Prepared by the esterification of 4-amino-2-chlorobenzoic acid with methanol in the presence of an acid catalyst. Alternatively, it can be synthesized by the chlorination of methyl 4-aminobenzoate followed by reduction of the resulting nitro compound. |
| Safety Information | May cause skin and eye irritation. Handle with care and wear appropriate personal protective equipment. Avoid ingestion and contact with mucous membranes. |
