Methoxy-polyethylene glycol-maleimide
Other Pharmaceutical 2025-03-04
CAS: 724722-89-8
Catalog: HY-W020780
| Aspect | Details |
|---|---|
| Structure | Consists of a methoxy-terminated PEG chain and a maleimide functional group. The PEG chain provides hydrophilicity and biocompatibility, while the maleimide group offers high reactivity. |
| Applications | Widely used in bioconjugation, drug delivery, and surface modification. It can be conjugated to biomolecules like proteins, peptides, and antibodies through thiol-maleimide coupling. |
| Reactivity | The maleimide group readily reacts with thiol (-SH) groups under mild conditions (pH 6.5-7.5), forming stable thioether bonds. |
| Molecular Weight | Available in various molecular weights, commonly ranging from 500 to 20,000 Da, with specific weights like 2k, 3.4k, 5k, and 10k. |
| Storage Conditions | Should be stored at -20°C in a dry, light-protected environment to maintain stability and activity. Avoid frequent freeze-thaw cycles. |
| Purity | Typically has a purity of >95%, ensuring reliable performance in bioconjugation and other applications. |
| Solubility | Soluble in water, chloroform, and DMSO at concentrations up to 10 mg/mL. |
| Stability | Stable for up to 1 year when stored properly at -20°C and kept dry. |
| Customization | Can be customized for specific molecular weights and applications. |
Disclaimer: The above content is for reference and communication only among industry insiders, and does not guarantee its accuracy or completeness. According to relevant laws and regulations and the regulations of this website, units or individuals who purchase related items should obtain valid qualifications and qualification conditions.
