Metadoxine
Active Pharmaceutical Ingredients 2025-03-03
Catalog ID80020729
CAS NO.74536-44-0
Purity 96%
MDL NumberMFCD08704232
EINEC277-913-8
Molecular FormulaC8H11NO3.C5H7NO3
Molecular Weight298.2918
Melting point: 96~102°C
| Category | Information |
|---|---|
| Chemical Properties | Metadoxine is a compound composed of pyroglutamic acid and vitamin B6, with the molecular formula C₁₃H₁₈N₂O₆ and a molecular weight of 298.3 g/mol. |
| Physical Properties | It appears as an off-white powder. |
| Mechanism of Action | Metadoxine acts as a synthetic antioxidant by forming traps that reduce free radicals. It also has effects on the 5-HT2B receptor and is used to treat acute alcohol intoxication and chronic alcoholism. |
| Clinical Uses | – Alcohol Intoxication: Used to treat acute alcohol intoxication.<br>- Chronic Alcoholism: Helps improve liver function in patients with chronic alcoholism.<br>- Other Uses: Investigated for potential use in treating attention deficit and hyperactivity disorders (ADHD) and fragile X syndrome. |
| Pharmacological Classification | Classified as an alcohol deterrent and liver therapy agent. |
| Adverse Effects | Generally considered safe with rare adverse events reported in clinical trials. |
| Storage Conditions | Specific storage conditions are not widely documented, but it is typically stored in a cool, dry place to maintain stability. |
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