Meptazinol hydrochloride
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Category：Active Pharmaceutical Ingredients Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
Catalog ID80020188
CAS NO.59263-76-2
Purity 98%
MDL NumberMFCD00941476
EINEC261-683-0
Molecular formula C15H23NO.HCl
Molecular weight 269.81
Melting point: 190~194°C
| Category | Information |
|---|---|
| Chemical Properties | – Molecular Formula: C₁₅H₂₃NO·HCl<br>- Molecular Weight: 269.81 g/mol |
| Physical Properties | – Appearance: White solid |
| Mechanism of Action | – Acts as a partial agonist at the μ₁ opioid receptor, providing analgesic effects.<br>- Exhibits central cholinergic activity, which may contribute to its analgesic properties.<br>- Has a lower propensity for respiratory depression and addiction compared to other opioids. |
| Clinical Uses | – Used for the treatment of moderate to severe pain, including postoperative pain, obstetric pain, and renal colic.<br>- Investigated for its potential in reducing opioid dependence and respiratory depression. |
| Pharmacokinetics | – Rapid absorption after intramuscular injection, with peak plasma concentration reached within 30 minutes.<br>- Plasma half-life is approximately 2 hours.<br>- Primarily excreted in urine as glucuronide conjugates. |
| Adverse Effects | – Common side effects include dizziness, nausea, vomiting, somnolence, sweating, tinnitus, and hot flashes.<br>- Less common side effects include leukocytosis and elevated triglycerides. |
| Storage Conditions | Store at -20°C for up to 3 years (powder); in solvent at -80°C for up to 1 year. |
| Solubility | – Soluble in water (27 mg/mL) and DMSO (50 mg/mL). |
| Synonyms | – Meptazinol HCl<br>- 3-(3-Ethyl-1-methyl-1H-hexahydropyridazin-3-yl)phenol hydrochloride |
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