Levomefolic acid CAS: 31690-09-2
Category：Chemical Intermediates
Introduction
CAS: 31690-09-2
Purity: ≥99%
Capacity: 200mt/year
MOQ: 100g
Application: Organic Intermediate
Standard: Enterprise export
Manufacturer: Jinan Finer Chemical Co., Ltd
Synonyms: (6S)-5-Methyltetrahydrofolic acid
(S)-N-[4-[[(2-Amino-1.4.5.6.7.8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
Molecular Formula: C20H25N7O6
Molecular Weight: 459.46
CAS Registry Number: 31690-09-2
Density: 1.62
Levomefolic acid, also known as 5-methyltetrahydrofolate (5-MTHF), is a naturally occurring and biologically active form of folate. With the CAS number 31690-09-2, it has the chemical formula C20H25N7O6 and a molecular weight of 459.46 g/mol. Levomefolic acid exists as a solid and is primarily used in pharmaceutical preparations due to its essential role in folate metabolism. It can be converted directly into the active form of folate used by the body, bypassing metabolic steps that may be impaired in certain individuals. This makes levomefolic acid particularly beneficial for those with mutations in the MTHFR gene, which affects folate metabolism.
| Property Category | Details |
|---|---|
| Chemical Name | Levomefolic acid |
| CAS Number | 31690-09-2 |
| Molecular Formula | C20H25N7O6 |
| Molecular Weight | 459.46 g/mol |
| Physical Properties | |
| – Appearance | Solid, typically grayish-white to light green |
| – Melting Point | 215-218 °C |
| – Density | 1.62 g/cm³ |
| – Solubility | Slightly soluble in alkaline solutions (with heating and sonication), DMSO (slightly) |
| Chemical Properties | |
| – pH | Stable in a range suitable for pharmaceutical formulations |
| – Stability | Stable under recommended storage conditions (-20 °C to -80 °C) |
| – LogP | -2.61 (indicating hydrophilic nature) |
| – Refractive Index | 1.733 |
| – Uses | Pharmaceutical active ingredient, food additive, for prevention of neural tube defects, etc. |
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