Lercanidipine HCl
We are a manufacturer based in China, specializing in high-quality Lercanidipine HCl for industrial clients worldwide. Technical support and custom formulation available.
Category：Active Pharmaceutical Ingredients | Brand：MT
Factory Direct
7-30 Days Lead Time
MOQ: 100KG
Global Export
Introduction
Catalog ID80017924
CAS NO.132866-11-6
Purity 98+%
MDL NumberMFCD07773089
olecular Formula C36H41N3O6.HCl
Molecular Weight 648.1882
Melting point: 119~123°C
| Category | Details |
|---|---|
| Chemical Properties | Molecular formula: C36H41N3O6·HCl<br> Molecular weight: 648.19 g/mol |
| Physical Properties | Appearance: Pale-yellow powder |
| Mechanism of Action | Lercanidipine is a third-generation, lipophilic, dihydropyridine calcium channel blocker. It selectively blocks L-type calcium channels in vascular smooth muscle, causing peripheral vasodilation and reducing blood pressure. It also has antioxidant, anti-inflammatory, and anti-apoptotic properties. |
| Therapeutic Uses | Antihypertensive: Used alone or in combination with ACE inhibitors to treat hypertension.<br> Neuroprotective: Demonstrates neuroprotective effects in ischemic-reperfusion injury models.<br> Renoprotective: Exhibits renoprotective effects. |
| Pharmacokinetics | Long-acting with a slower onset and longer duration of action compared to other calcium channel antagonists. |
| Formulations | Available as tablets for oral administration. |
| Storage Conditions | Store at -20°C for 3 years (powder); -80°C for 1 year (in solvent). |
| Safety Information | Generally well-tolerated with low incidence of adverse effects |
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