Active Pharmaceutical Ingredients

Catalog ID80017924

CAS NO.132866-11-6

Purity 98+%

MDL NumberMFCD07773089

olecular Formula C36H41N3O6.HCl

Molecular Weight 648.1882

Melting point: 119~123°C

Category	Details
Chemical Properties	Molecular formula: C36H41N3O6·HCl<br> Molecular weight: 648.19 g/mol
Physical Properties	Appearance: Pale-yellow powder
Mechanism of Action	Lercanidipine is a third-generation, lipophilic, dihydropyridine calcium channel blocker. It selectively blocks L-type calcium channels in vascular smooth muscle, causing peripheral vasodilation and reducing blood pressure. It also has antioxidant, anti-inflammatory, and anti-apoptotic properties.
Therapeutic Uses	Antihypertensive: Used alone or in combination with ACE inhibitors to treat hypertension.<br> Neuroprotective: Demonstrates neuroprotective effects in ischemic-reperfusion injury models.<br> Renoprotective: Exhibits renoprotective effects.
Pharmacokinetics	Long-acting with a slower onset and longer duration of action compared to other calcium channel antagonists.
Formulations	Available as tablets for oral administration.
Storage Conditions	Store at -20°C for 3 years (powder); -80°C for 1 year (in solvent).
Safety Information	Generally well-tolerated with low incidence of adverse effects

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