L-Ornithine Hydrochloride CAS 3184-13-2

Amino Acids 2025-03-02

Parameter Specifications
CAS Registry Number 3184-13-2
Chemical Formula C₅H₁₂N₂O₂·HCl
Molar Mass 168.62 g/mol
Grade Pharmaceutical/Food Grade
Bioavailability >98% (oral absorption)
Pharmacological Role Urea cycle activator; ammonia scavenger; precursor for arginine/proline
Clinical Indications Hyperammonemia, hepatic encephalopathy, muscle wasting, wound healing
Therapeutic Effects Reduces fatigue; supports protein synthesis; enhances detoxification
Dosage Guidelines 2-8 g/day divided doses (oral); adjust for renal function
Contraindications Urea cycle disorders; end-stage renal disease
Storage Conditions Cool, dry environment; protect from light
Synergistic Agents α-Ketoglutarate, citrulline, aspartate

Description

L-ornithine hydrochloride is a white crystalline powder. It is soluble in organic solvents such as methanol, ethanol, and DMSO.

Application

L-ornithine hydrochloride is a free amino acid, which plays an important role in the urea cycle and is also important for the treatment of excess nitrogen. L-ornithine hydrochloride is an important basic raw material for the pharmaceutical industry, an important metabolite in cells, and has an important regulatory effect on the elimination of liquid ammonia in organisms. L-ornithine hydrochloride has the effects of curing liver cirrhosis, enhancing human immunity, and resisting fatigue.

Specification

Appearance White crystals or crystalline powder Identification Infrared absorption Specific rotation[α]20D +23.0°~ +25.0° State of solution ≥98.0% Ammonium ≤0.02% Sulfate ≤0.020% Iron ≤10ppm Heavy metals (Pb) ≤10ppm Arsenic (As2O3) ≤1ppm Other amino acids Chromatographically undetectable Loss on drying ≤0.20% Residue on ignition ≤0.10% Assay 99.0~101.0% PH 5.0-6.0 Packing 25kg/drum or as per requirement. Storage Store in a cool, dry place.

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