L-BIOPTERIN CAS:22150-76-1
Package: 1g,5g,10g,1kg..or according to requirements. Storage: in a dry and ventilated warehouse; keep away from sunshine and moisture.
Name
6-Biopterin
Synonyms
6-BiopterinL-BiopterinD-eryth...
Category：Pharmaceutical Materials
Introduction
Package: 1g,5g,10g,1kg..or according to requirements. Storage: in a dry and ventilated warehouse; keep away from sunshine and moisture.
| Name | 6-Biopterin |
| Synonyms | 6-Biopterin L-Biopterin D-erythro-Biopterin L-Biopterin(6-Biopterin) 2-amino-6-(1,2-dihydroxypropyl)pteridin-4(1H)-one 2-amino-7-(1,2-dihydroxypropyl)pteridin-4(1H)-one 2-amino-6-(1,2-dihydroxypropyl)-1H-pteridin-4-one 2-Amino-4-hydroxy-6-(1,2-dihydroxypropyl)pteridine 2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]pteridin-4(1H)-one 2-Amino-6-[(1S,2R)-1,2-dihydroxypropyl]pteridin-4(1H)-one 2-Amino-6-[(1S,2R)-1,2-dihydroxypropyl]pteridine-4(3H)-one [S-(R*,S*)]-2-amino-6-(1,2-dihydroxypropyl)-1H-pteridin-4-one L-Biopterin,2-Amino-4-hydroxy-6-(1,2-dihydroxypropyl)pteridine (1R,2S)-Biopterin, 2-Amino-4-hydroxy-6-(1,2-dihydroxypropyl)pteridine, L-erythro-6-(1,2-Dihydroxypropyl)pterin |
| CAS | 22150-76-1 |
| EINECS | 244-807-8 |
| InChI | InChI=1/C9H11N5O3/c1-3(15)6(16)4-2-11-5-7(12-4)13-9(10)14-8(5)17/h2-3,6,15-16H,1H3,(H3,10,12,13,14,17) |
| Molecular Formula | C9H11N5O3 |
| Molar Mass | 237.22 |
| Density | 1.3472 (rough estimate) |
| Melting Point | >210°C dec. |
| Boling Point | 379.74°C (rough estimate) |
| Specific Rotation(α) | D24 -50° (c = 0.4 in 0.1N HCl); D24 -26° (c = 0.92 in 0.1N NaOH) |
| Flash Point | 295.2°C |
| Solubility | Bioptein is very slightly soluble in water. The solubility of biopterin is about 0.01 |
| Vapor Presure | 1.4E-13mmHg at 25°C |
| Appearance | Crystalline solid |
| Color | White to Light Yellow |
| Merck | 13,1229 |
| BRN | 87860 |
| pKa | 13.18±0.20(Predicted) |
| Storage Condition | 2-8°C |
| Stability | Hygroscopic |
| Refractive Index | 1.7610 (estimate) |
| MDL | MFCD00036787 |
| Use | 6-Biopterin is an oxidation product from the melanogenesis regulating cofactor (6R)5,6,7,8 tetrahydrobiopterin (6-BH4). In vitro, 6-Biopterin is cytotoxic to melanocytes. However, in vivo, 6-Biopterin is rapidly and sequentially reduced back to 6-GH4 |
| In vitro study | 6-biopterin is extremely cytotoxic to human melanocytes under in vitro conditions. Thioredoxin reductase has the capacity to reduce 6-biopterin to q-BH2 where further reduction to 6-BH4 follows via dihydropteridine reductase or reduced glutathione. (6R)5,6,7,8 tetrahydrobiopterin undergoes redox-cycling by its oxidation to quinonoid dihydrobiopterin and to 6-biopterin through consecutive two electron oxidation reactions. |
,Disclaimer: The above content is for reference and communication only among industry insiders, and does not guarantee its accuracy or completeness. According to relevant laws and regulations and the regulations of this website, units or individuals who purchase related items should obtain valid qualifications and qualification conditions.
