L-Aspartic Acid
Amino Acids 2025-03-11
| Subheading | Details |
|---|---|
Basic Information |
|
| Name | L-Aspartic Acid |
| Other Names | Acide Aspartique, Asp, Asparta |
| Chemical Formula | C4H7NO4 |
| Molecular Weight | 133.10 g/mol |
| CAS Number | 56-84-8 |
| Appearance | White crystal or crystalline powder, slightly sour in taste |
Physical Properties |
|
| Solubility | Soluble in boiling water, slightly soluble in water at 25℃ (0.5%), freely soluble in dilute acid and sodium hydroxide solution, insoluble in ethanol and ethyl ether |
| Melting Point | Deposes when heated to 270 ℃ |
| Isoelectric Point | 2.77 |
| Specific Rotation | Associated with the soluble solvent; dextral in acid and water solutions, levorotary in alkali solutions |
Chemical Reactions |
|
| Reactions | Combines with HNO2. alcohol, or acyl chloride to produce L-malic acid, esters, and amides, respectively |
Occurrence |
|
| Natural Sources | Ingredient of unripe sugarcane and beet molasses |
Uses |
|
| Medical Uses | Used as an electrolyte supplement for aminophenol transfusion and inorganic ion supplement (K+, Ca+, etc.). Potassium magnesium aspartate injection or oral solution can be used for arrhythmia, premature beat, tachycardia, hypokalemia, hypomagnesemia, heart failure, myocardial infarction, angina pectoris, hepatitis, cirrhosis, and other diseases caused by cardiac glycoside poisoning. |
| Non-Medical Uses | Used for athletic performance, fatigue reduction, and muscle strength enhancement, although scientific evidence supporting these uses is limited. |
Safety Information |
|
| Toxicity | Low toxicity; cannot be injected without dilution. Use with caution in patients with renal insufficiency and atrioventricular conduction block. |
| Special Precautions | Avoid use during pregnancy and breastfeeding due to potential risks of brain defects in newborns (based on animal research). Not recommended for infants. |
