L-Abrine
Active Pharmaceutical Ingredients 2025-03-03
Catalog ID 80019339
CAS NO.526-31-8
Purity 99%
MDL NumberMFCD00005645
EINEC208-388-5
Molecular formula C12H14N2O2
Molecular weight 218.25
| Category | Details |
|---|---|
| Chemical Properties | L-Abrine (N-Methyl-L-tryptophan) is an indole alkaloid with the molecular formula C12H14N2O2 and a molecular weight of 218.25. It appears as an off-white to light yellow crystalline powder. |
| Physical Properties | Melting point >300°C (decomposition). Density: 1.272±0.06 g/cm³ at 20°C. Refractive index: 65° (C=1, 0.5mol/L NaOH). |
| Solubility | Soluble in methanol (1g in about 100ml), soluble in dilute acids and bases, slightly soluble in water, and insoluble in ether. |
| Toxicity | L-Abrine is a toxic compound. It is harmful if swallowed, inhaled, or comes into contact with skin. It is found in the seeds of Abrus precatorius, a plant known for its highly toxic properties. |
| Applications | L-Abrine is used as a biomarker for abrin (a highly toxic protein) exposure. It is also used in biochemical research for its ribosome-inhibiting properties. |
| Storage Conditions | Store under inert gas (e.g., nitrogen or argon) at 2–8°C. |
| Environmental Concerns | The substance may be harmful to the environment, particularly to aquatic life. |
| Synthesis | L-Abrine can be synthesized by methylation of L-tryptophan using sodium amide and iodomethane |
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