Ketotifen fumarate CAS NO.34580-14-8
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Category：Active Pharmaceutical Ingredients Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
Catalog ID80017120
CAS NO.34580-14-8
Purity 96%
MDL NumberMFCD00079394
EINEC252-100-0
Molecular FormulaC19H19NOs.C4H4O4
Molecular Weight425.4974
| Aspect | Details |
|---|---|
| Chemical Structure | Ketotifen fumarate is a tricyclic antihistamine and mast cell stabilizer. Its chemical formula is C₂₀H₁₉NO₂·C₄H₄O₄, with a molecular weight of 389.41 g/mol. |
| Mechanism of Action | It acts as a selective histamine H₁ receptor antagonist, blocking the effects of histamine released during allergic reactions. Additionally, it stabilizes mast cells, preventing the release of inflammatory mediators such as histamine, leukotrienes, and prostaglandins. |
| Clinical Uses | Ketotifen fumarate is used for the treatment of allergic conditions, including allergic rhinitis, asthma, and allergic conjunctivitis. It is also used in the management of chronic urticaria and atopic dermatitis. |
| Formulations | Available as tablets, syrups, eye drops, and nasal sprays. It can also be formulated into extended-release tablets for once-daily dosing. |
| Storage Conditions | Store at room temperature (15–30°C) in a dry place, protected from light. |
| Side Effects | Common side effects include drowsiness, dry mouth, and gastrointestinal disturbances. Less common side effects may include headache, blurred vision, and weight gain. |
| Special Precautions | Use with caution in patients with liver or kidney impairment. Avoid driving or operating machinery if drowsiness occurs. |
| Regulatory Status | Approved for use in various countries for the treatment of allergic conditions. It is available over-the-counter in some regions |
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