Ivabradine hydrochloride side chain

Pharmaceutical Materials 2025-03-02

Chemical Name: Ivabradine hydrochloride side chain

Molecular Structure: Part of the Ivabradine hydrochloride molecule, contributing to its pharmacological activity

Function: As part of Ivabradine hydrochloride, it aids in the inhibition of the If current in the sinoatrial node

Ivabradine hydrochloride side chain, a crucial component in the synthesis of ivabradine hydrochloride (CAS number 148849-67-6), is an important pharmaceutical intermediate. Ivabradine hydrochloride itself is a selective and specific heart rate inhibitor, primarily used in the treatment of patients with angina pectoris who are intolerant to β-blockers or have heart failure. The side chain plays a vital role in the pharmacological activity of ivabradine hydrochloride by influencing its interaction with the hyperpolarization-activated cyclic nucleotide-gated (HCN) channel.

Property Category Details
Chemical Component Ivabradine hydrochloride side chain
Associated Drug Ivabradine hydrochloride
Physical Properties
Appearance Part of a complex molecular structure
Chemical Properties
Functional Group Part of a heterocyclic structure
Reactivity Influences the pharmacological activity of ivabradine hydrochloride
Stability Stable within the context of the ivabradine hydrochloride molecule

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