Active Pharmaceutical Ingredients

Catalog ID 80019148

CAS NO.55453-87-7

Purity 98+%

MDL NumberMFCD00242952

Molecular Formula C16H12O4

Molecular Weight 268.2641

Melting point: 131~132.5°C

Category	Details
Chemical Properties	Isoxepac is a beige solid with a molecular formula of C16H12O4 and a molecular weight of 268.26. It has a melting point of 130–132°C.
Physical Properties	It is slightly soluble in water but soluble in methanol. It appears as a white to light yellow or light orange solid.
Pharmacological Effects	Isoxepac is a nonsteroidal anti-inflammatory agent (NSAID) with anti-inflammatory, analgesic, and antipyretic properties. It has been studied in various animal models and is used to treat conditions such as allergic rhinitis, urticaria, and skin diseases with itching symptoms.
Mechanism of Action	Although the exact mechanism of action is not fully described, Isoxepac likely exerts its anti-inflammatory effects through pathways similar to other NSAIDs, such as inhibiting prostaglandin synthesis.
Synthesis	Isoxepac can be synthesized from p-hydroxyphenylacetic acid and phthalide through condensation and cyclization reactions, followed by purification.
Safety and Handling	Isoxepac is classified as a toxic substance. It has an oral LD50 of 199 mg/kg in rats. It should be stored in a sealed container at room temperature.
Storage Conditions	Store in a cool, dry place at room temperature.

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