Isoxepac
Active Pharmaceutical Ingredients 2025-03-03
Catalog ID 80019148
CAS NO.55453-87-7
Purity 98+%
MDL NumberMFCD00242952
Molecular Formula C16H12O4
Molecular Weight 268.2641
Melting point: 131~132.5°C
| Category | Details |
|---|---|
| Chemical Properties | Isoxepac is a beige solid with a molecular formula of C16H12O4 and a molecular weight of 268.26. It has a melting point of 130–132°C. |
| Physical Properties | It is slightly soluble in water but soluble in methanol. It appears as a white to light yellow or light orange solid. |
| Pharmacological Effects | Isoxepac is a nonsteroidal anti-inflammatory agent (NSAID) with anti-inflammatory, analgesic, and antipyretic properties. It has been studied in various animal models and is used to treat conditions such as allergic rhinitis, urticaria, and skin diseases with itching symptoms. |
| Mechanism of Action | Although the exact mechanism of action is not fully described, Isoxepac likely exerts its anti-inflammatory effects through pathways similar to other NSAIDs, such as inhibiting prostaglandin synthesis. |
| Synthesis | Isoxepac can be synthesized from p-hydroxyphenylacetic acid and phthalide through condensation and cyclization reactions, followed by purification. |
| Safety and Handling | Isoxepac is classified as a toxic substance. It has an oral LD50 of 199 mg/kg in rats. It should be stored in a sealed container at room temperature. |
| Storage Conditions | Store in a cool, dry place at room temperature. |
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