Isopropyl chloroacetate

We are a manufacturer based in China, specializing in high-quality Isopropyl chloroacetate for industrial clients worldwide. Technical support and custom formulation available.

Category:Chemical Additives  |  Brand:MT

Factory Direct 7-30 Days Lead Time MOQ: 100KG Global Export

Introduction

​Isopropyl Chloroacetate

Chemical Formula: C₅H₉ClO₂
Structure: Ester of ​chloroacetic acid and ​isopropanol, with:

  • A ​chloroacetate group (-OCOCH₂Cl).
  • An ​isopropyl group (-CH(CH₃)₂).
  • Combines properties of esters and alkyl halides.

​Physical Properties

  • ​Appearance: Clear, colorless to pale yellow liquid.
  • ​Odor: Mild ester-like odor.
  • ​Reactivity:
    • ​Moisture-sensitive: Reacts with water/humidity.
    • Highly reactive in nucleophilic substitution and esterification reactions.

​Applications

  1. ​Organic Synthesis:
    • Reagent for introducing ​chloroacetyl groups into molecules.
    • Production of ​pharmaceuticals, ​agrochemicals, and fine chemicals.
  2. ​Biomolecule Modification:
    • Functionalizes peptides and biomolecules via alkylation.

​Safety Considerations ⚠️

  • ​Health Hazards:
    • Causes ​severe irritation to skin, eyes, and respiratory system.
  • ​Handling:
    • Use ​PPE (gloves, goggles, respirator) and work in a ​fume hood.
  • ​Storage:
    • Store in a ​cool, dry, airtight container away from ​moisture and incompatible substances (e.g., bases, oxidizers).

Summary:
Isopropyl chloroacetate’s ​reactivity and ​chloroacetyl-transfer capability make it vital in drug synthesis and biomolecule engineering. Strict ​safety protocols are mandatory due to its corrosive and moisture-sensitive nature.

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