Isonicotinic acid
Pharmaceutical Materials 2025-03-02
CAS Number: 55-22-1
Molecular Formula: C6H5NO2
Molecular Weight: 123.11 g/mol
Appearance: White crystalline solid
Usage: Primarily used as a pharmaceutical intermediate in the manufacture of anti-tuberculosis drugs, such as Isoniazid, and also for the synthesis of amides, hydrazides, esters, and other derivatives.
Disclaimer: The above content is for reference and communication only among industry insiders, and does not guarantee its accuracy or completeness. According to relevant laws and regulations and the regulations of this website, units or individuals who purchase related items should obtain valid qualifications and qualification conditions.
| Category | Details |
|---|---|
| Chemical Name | Isonicotinic acid |
| Synonyms | 4-Picolinic acid, Pyridine-4-carboxylic acid, Isonicotinate |
| CAS Number | 55-22-1 |
| Molecular Formula | C6H5NO2 |
| Molecular Weight | 123.11 g/mol |
| Appearance | White crystalline powder |
| Melting Point | ≥300 °C (lit.) |
| Flash Point | 193.3±20.4 °C |
| Solubility | Soluble in hot water, ethanol, and other organic solvents; slightly soluble in cold water |
| Chemical Properties | Isonicotinic acid is an organic compound belonging to the pyridine carboxylic acid family. It is a colorless or white crystalline powder with a slight odor. It is stable under normal conditions and is not prone to decomposition. |
| Applications | – Used as an intermediate in the synthesis of heterocyclic compounds and drugs, such as isoniazid (an anti-tuberculosis drug). – Used in the preparation of isonicotinyl hydrazide and other derivatives. – Potential applications in the pesticide industry for the synthesis of specific pesticides. |
| Safety Information | Isonicotinic acid is irritating to the skin and eyes. It should be handled with caution to avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water and seek medical attention if necessary. Store in a cool, dry place away from heat, sparks, and open flames. |
