Active Pharmaceutical Ingredients

Catalog ID80019093

CAS NO.961-29-5

Purity 98%

MDL NumberMFCD00075907

Molecular Formula C15H12O4

Molecular Weight 256.2534

Melting point: 190~200°C

Category	Details
Chemical Properties	Yellow crystalline powder. Molecular formula: C15H12O4. Molecular weight: 256.25.
Physical Properties	Melting point: 206–210°C. Soluble in methanol, ethanol, and DMSO.
Biological Activities	Antioxidant and Anti-inflammatory: Exhibits antioxidant and anti-inflammatory properties.<br> Antitumor Activity: Demonstrates antitumor effects by inhibiting cell proliferation and inducing apoptosis in various cancer cell lines.<br> Aldehyde Reductase Inhibition: Inhibits aldose reductase with an IC50 of 320 nM, potentially preventing diabetic complications.<br> Skin Whitening: Inhibits tyrosinase activity, useful as a skin whitening agent with an IC50 of 8.1 μM.
Mechanism of Action	Antitumor: Induces cell cycle arrest and apoptosis through mechanisms involving increased intracellular calcium levels and mitochondrial depolarization.<br> Anti-inflammatory: Inhibits nitric oxide production in LPS-stimulated macrophages.<br> Aldehyde Reductase Inhibition: Prevents sorbitol accumulation in human red blood cells, with an IC50 of 2.0 μM.
Applications	Used in pharmaceuticals for its antioxidant, anti-inflammatory, and antitumor properties. Also used in cosmetics as a skin whitening agent.
Storage Conditions	Store at 2–8°C, protected from light and moisture.

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