Isochlorogenic acid A
Active Pharmaceutical Ingredients 2025-03-03
Catalog ID80021370
CAS NO.2450-53-5
Purity 98%
MDL NumberMFCD00951290
Molecular Formula C25H24O12
Molecular Weight 516.45
| Item | Information |
|---|---|
| Chemical Name | Isochlorogenic acid A (3,5-Dicaffeoylquinic acid) |
| CAS Number | 2450-53-5 |
| Molecular Formula | C₂₅H₂₄O₁₂ |
| Molecular Weight | 516.46 |
| Physical Properties | – Appearance: Off-white to yellow/brown crystalline solid.<br>- Melting Point: >175°C (dec.).<br>- Density: 1.0±0.1 g/cm³ (predicted).<br>- Boiling Point: 826.2±65.0 °C (predicted). |
| Solubility | – DMSO: Slightly soluble.<br>- Methanol: Slightly soluble.<br>- Water: Insoluble. |
| Storage Conditions | -20°C. |
| Biological Activity | – Antioxidant Activity: Exhibits strong free radical scavenging activity.<br>- Anti-inflammatory Activity: Inhibits NO production in LPS-stimulated RAW 264.7 cells.<br>- Antimicrobial Activity: Inhibits Giardia lamblia LeuRS activity with an IC₅₀ of 5.82 µg/mL.<br>- Cytotoxic Activity: Promotes melanin synthesis in B16 cells. |
| Sources | Naturally found in plants such as Lonicera japonica (honeysuckle), Artemisia argyi, and Suaeda glauca. |
| Applications | – Used in research for its antioxidant, anti-inflammatory, and antimicrobial properties.<br>- Used as a standard for analytical and pharmacological studies.<br>- Potential use in the treatment of cognitive disorders and as a hepatoprotective agent. |
| Safety Information | – Hygroscopic.<br>- Store in a cool, dry place and protect from light.<br>- For research use only. |
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