Iomapidol
Active Pharmaceutical Ingredients 2025-03-03
English Synonyms (S)-N,N′-Bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-5-lactamidoisophthalamide
Catalog ID92828
CAS NO.60166-93-0
Purity 98+%
MDL NumberMFCD00867931
Molecular Formula C17H22I3N3O8
Molecular Weight 777.085
Melting point:>320°C (dec)
Boiling point:785.3°C at 760 mmHg
Flash point:428.8°C
| Category | Content |
|---|---|
| Generic Name | Iopamidol (Iomapidol) |
| Chemical Formula | C17H22I3N3O8 |
| Molecular Weight | 777.1 g/mol |
| Mechanism of Action | Iopamidol is a nonionic iodinated contrast agent used to enhance the visibility of blood vessels and other tissues during imaging procedures such as computed tomography (CT) and angiography. |
| Indications | – Used for intravascular injection in diagnostic imaging procedures to visualize blood vessels and other structures.<br>- Also used in intrathecal administration for myelography and contrast enhancement in neuroradiology. |
| Dosage Forms | Injectable solutions of various concentrations (e.g., 41%, 51%, 61%, 76%). |
| Administration | – Administered via intravascular injection for CT scans and angiography.<br>- Can also be administered intrathecally for myelography. |
| Clinical Uses | – Enhances the visibility of blood vessels, tumors, and other structures during imaging.<br>- Used in the diagnosis of cardiovascular diseases, neurological disorders, and other conditions requiring detailed imaging. |
| Safety Profile | – Generally well-tolerated with a low incidence of adverse reactions.<br>- Rarely causes allergic reactions or other complications. |
| Environmental Impact | – Iopamidol may be released into the environment through waste streams from production and use.<br>- It is not easily biodegradable and may persist in water and soil. |
| Developer | Developed by Bracco and Fresenius Kabi |
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