Introduction of Methyldithiocarbazate

News 2025-04-09

Uses of Methyldithiocarbazate

Methyldithiocarbazate (CAS No. 5397-03-5) is a versatile compound with applications spanning pharmaceuticals, agrochemicals, and materials science. Its key uses include:

  1. Pharmaceutical Intermediate:
    • Serves as a building block for synthesizing antitumor agents, such as platinum complexes with activity against breast and colon cancer cell lines.
    • Utilized in the development of thiosemicarbazone derivatives, which exhibit antimicrobial, antifungal, and antiviral properties.
  2. Agrochemicals:
    • Acts as a precursor for pesticides and herbicides, leveraging its reactivity in forming stable metal complexes.
  3. Coordination Chemistry:
    • Forms stable complexes with transition metals (e.g., Ni, Cu, Zn, Pd), making it valuable in catalysis and materials research.
  4. Analytical Chemistry:
    • Functions as a chelating agent for metal ions, aiding in separation and detection processes.
  5. Material Science:
    • Contributes to the synthesis of polymers, dyes, and advanced materials with tailored optical or electronic properties.

Physical and Chemical Properties of Methyldithiocarbazate

Property Value
CAS No. 5397-03-5
Molecular Formula C₂H₆N₂S₂
Molecular Weight 122.21 g/mol
Appearance White to off-white crystalline solid
Melting Point 79–81°C
Boiling Point Decomposes before boiling
Density 1.31 g/cm³
Solubility Soluble in ethanol, methanol, DMSO; slightly soluble in water
pKa 9.15 (approximate, for hydrazine nitrogen)
Stability Stable under inert atmosphere; hydrolyzes in acidic conditions