Imazodan
Active Pharmaceutical Ingredients 2025-03-03
Catalog ID80019626
CAS NO.76497-13-7
Purity 96%
MDL NumberMFCD00864948
Molecular Formula C25H30N4O9S2
Molecular Weight 594.66
| Category | Information |
|---|---|
| Chemical Properties | – Molecular Formula: C₁₃H₁₂N₄O<br>- Molecular Weight: 240.26 g/mol |
| Mechanism of Action | – PDE III Inhibition: Imazodan is a selective inhibitor of phosphodiesterase III (PDE III), which increases myocardial contractility by blocking the degradation of cAMP, thereby improving cardiac function.<br>- Vasodilator: Acts as a peripheral vasodilator, reducing peripheral resistance. |
| Clinical Uses | – Cardiovascular Diseases: Used for treating chronic heart failure and improving cardiac contractility.<br>- Research: Investigated for its potential in cardiovascular research and as a positive inotropic agent. |
| Physical Properties | – Appearance: Light yellow to yellow powder.<br>- Melting Point: 218°C.<br>- Solubility: Soluble in DMSO (28.57 mg/mL; 118.91 mM; ultrasonic and adjust pH to 7 with 1 M HCl). |
| Storage Conditions | – Powder: Store at room temperature for up to 3 years.<br>- In Solvent: -80°C for 2 years; -20°C for 1 year. |
| Synonyms | – CI-914.<br>- Imazodanum.<br>- 6-(4-(1H-imidazol-1-yl)phenyl)-4,5-dihydropyridazin-3(2H)-one |
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