Active Pharmaceutical Ingredients

Catalog ID80019702

CAS NO.83-49-8

Purity 98%

MDL NumberMFCD00003681

EINEC201-483-2

Molecular formula C24H40O4

Molecular weight 392.572

Melting point: 200~201℃

Category	Information
Chemical Properties	– Molecular Formula: C₂₄H₄₀O₄<br>- Molecular Weight: 384.58 g/mol<br>- IUPAC Name: (4R)-4-$(3R,5R,6S,8S,9S,10R,13R,14S,17R)-3,6-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta\text{[}a$phenanthren-17-yl]pentanoic acid
Physical Properties	– Appearance: White crystalline powder<br>- Melting Point: >235°C (decomposition)
Mechanism of Action	– Acts as a bile acid with potential signaling roles in lipid metabolism and glucose homeostasis.<br>- Promotes m6A modification of ETV4 mRNA, enhancing its stability and translation, leading to anti-fibrotic effects.<br>- Facilitates nuclear localization of PPARα, enhancing fatty acid oxidation and improving nonalcoholic fatty liver disease (NAFLD).
Clinical Uses	– Investigated for treating cholestatic liver fibrosis by targeting ETV4 expression.<br>- Studied for its potential in improving NAFLD by enhancing PPARα function.<br>- May help in reducing gallstone formation, hyperlipidemia, and atherosclerosis.
Storage Conditions	Store in a cool, dry place, protected from moisture.
Synonyms	– Hyodesoxycholic acid<br>- HDCA<br>- 3α,6α-Dihydroxy-5β-cholanoic acid

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