Hydrogenated castor oil
Pharmaceutical Materials 2025-03-02
CAS Number: 8001-78-3
Molecular Formula: C57H110O9
Molecular Weight: 939.48 g/mol
Appearance: White to pale yellow powder, block, or flakes
Usage: Widely used as a thickening agent, hardening agent, and sustained-release agent in pharmaceutical preparations.
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| Category | Details |
|---|---|
| Chemical Name | Hydrogenated castor oil |
| Synonyms | Castor oil, hydrogenated; Hydrogenated castor oil (HCO); PPG Hydrogenated Castor Oil (for derivatives) |
| CAS Number | 8001-78-3 |
| EINECS Number | 232-292-2 |
| Appearance | White to light yellow powder, blocks, or flakes |
| Melting Point | 83-88°C |
| Acid Value | ≤4.0 |
| Hydroxyl Value | 145-165 |
| Iodine Value | ≤5.0 |
| Saponification Value | 176-182 |
| Chemical Properties | – Non-volatile, non-toxic, and stable. – Compatible with most natural plant waxes and animal waxes. – Has good emulsifying, dispersing, and solubilizing properties. |
| Applications | – Used as a thickening agent, hardening agent, and sustained-release agent in pharmaceutical preparations, such as ointments, suppositories, pills, and tablets. – As a lubricant in tablet formulations, improving the flowability of granules. – In cosmetics, it serves as an emulsifier, stabilizer, and skin-conditioning agent. – Applied in the textile industry as a softening agent and antistatic agent. |
| Storage Conditions | Store in a cool, dry place, away from fire, rain, and direct sunlight. Keep containers tightly closed and avoid contamination. |
| Safety Information | Considered safe for use in cosmetics and pharmaceuticals within specified concentrations. However, avoid contact with eyes and skin to prevent irritation. Follow proper handling and disposal procedures. |
