Hexafluoropropylene oxide

Pharmaceutical Materials 2025-03-03

CAS Number: 428-59-1

Molecular Formula: C3F6O

Molecular Weight: 166.02 g/mol

Appearance: Colorless odorless gas

Melting Point: -129 °C

Boiling Point: -28 °C (or -42.0±0.0 °C at 760 mmHg)

Density: 1.7±0.1 g/cm3 (or 1.88 g/mL at 25 °C)

Usage: Important intermediate of organic fluorine material.

 

Property Details
Chemical Name Hexafluoropropylene oxide
Synonyms HFPO; Perfluoropropylene oxide; Hexafluoropropene epoxide; trifluoro(trifluoromethyl)oxirane
CAS Number 428-59-1
EINECS Number 207-050-4
Molecular Formula C₃F₆O
Molecular Weight 166.02 g/mol
Physical State Colorless, odorless gas
Melting Point -129 °C
Boiling Point -42 °C
Density 1.7±0.1 g/cm³
Solubility Insoluble in water; solubility in organic solvents varies
Applications – Fluorinated Intermediate: Essential for synthesizing high-performance fluoropolymers, surfactants, and lubricants.
– Advanced Materials: Used in producing perfluoropolyether (PFPE) oils, fluorinated elastomers, and ion-exchange membranes.
– Specialty Chemicals: Critical for manufacturing fluorinated pharmaceuticals and agrochemicals.
Health & Safety – Toxicity: Highly reactive; liquid contact causes frostbite; vapors may displace oxygen, leading to asphyxiation.
– Handling: Requires explosion-proof equipment; store in cool, dry, well-ventilated areas.
– Regulatory Compliance: Classified as a hazardous material (UN 1956) under transport regulations.

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