Glabridin CAS No.59870-68-7
Pharmaceutical Materials 2025-03-20
CAS No.59870-68-7
Name
Glabridin
Synonyms
Glabridin
professional manufacturer Glabridin 59870-68-7
4-[(3R)-8.8-Dimethyl-3.4-dihydro-2H-pyrano[6.5-f]chromen-3-yl]benzene-1.3-diol
4-[(3R)-8.8-dimethyl-3.4-dihydro-2H,8H-pyrano[2.3-f]chromen-3-yl]benzene-1.3-diol
| Category | Information |
|---|---|
| Basic Information | |
| Name | Glabridin |
| Alternative Names | Glycyrrhizae Radix Extract,甘草黄酮, Guangancaoding |
| Chemical Formula | C20H20O4 |
| CAS Number | 59870-68-7 |
| Molecular Weight | 324.37 g/mol |
| Physical Properties | |
| Appearance | White to light brown powder |
| Melting Point | 154-158°C |
| Solubility | Insoluble in water; soluble in organic solvents such as DMSO, Ethanol, and DMF |
| Density | Approximately 1.257-1.3 g/cm³ |
| Chemical Properties | |
| Type | Isoflavan |
| Function | Can improve mitochondrial function and stimulate DNA synthesis in human endothelial cells |
| Biological Activities | |
| Antioxidant | Shows strong antioxidant activity, scavenging free radicals |
| Anti-inflammatory | Demonstrates anti-inflammatory effects by inhibiting the production of inflammatory cytokines |
| Antimicrobial | Has antibacterial properties against a range of bacteria |
| Antitumor | Inhibits the proliferation of cancer cells and induces apoptosis |
| Others | Anti-diabetic, anti-osteoporotic, cardioprotective, neuroprotective |
| Applications | |
| Cosmetics | Widely used as a skin-whitening agent in high-end cosmetic products |
| Pharmaceutical | Potential use in the development of drugs for treating inflammatory diseases and cancer |
| Safety Information | |
| Toxicity | Generally considered low in toxicity |
| Handling | Wear appropriate protective clothing and gloves during handling |
| Storage | Store in a cool, dry place, away from heat, and direct sunlight |
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