Furosemide CAS No.: 54-31-9

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Introduction

Molecular Formula: C12H11ClN2O5S

Molecular Weight: 330.7

CAS No.: 54-31-9

Name Furosemide
Synonyms Frusemide
FRUSEMIDE
FUROSEMID
FUROSEMIDE
Furosemide
LABOTEST-BB LT00244801
4-CHLORO-N-FURFURYL-5-SULFAMOYLANTHRANILIC ACID
4-chloro-n-furfuryl-5-sulfamoylanthranilic acid
2-furfurylamino-4-chloro-5-sulfamoylbenzoic acid
2-furfurylamino-4-chloro-5-sulfamoylbenzoic acid
5-(aminosulfonyl)-4-chloro-2-((2-furanylmethyl)amino)benzoic acid
5-[AMINOSULFONYL]-4-CHLORO-2-[(2-FURANYLMETHYL)AMINO]BENZOIC ACID
5-(AMINOSULPHONYL)-4-CHLORO-2-[(2-FURANYLMETHYL)AMINO]BENZOIC ACID
CAS 54-31-9
EINECS 200-203-6
InChI InChI=1/C12H11ClN2O5S/c13-9-5-10(15-6-7-2-1-3-20-7)8(12(16)17)4-11(9)21(14,18)19/h1-5,15H,6H2,(H,16,17)(H2,14,18,19)
InChIKey ZZUFCTLCJUWOSV-UHFFFAOYSA-N

Physico-chemical Properties

Molecular Formula C12H11ClN2O5S
Molar Mass 330.74
Density 1.606
Melting Point 220 °C (dec.) (lit.)
Boling Point 582.1±60.0 °C(Predicted)
Flash Point 11°C
Water Solubility Soluble in acetone, DMF or methanol. Slightly soluble in water
Solubility Practically insoluble in water, soluble in acetone, sparingly soluble in ethanol (96 per cent), practically insoluble in methylene chloride. It dissolves in dilute solutions of alkali hydroxides.
Appearance powder
Color White to Off-White
Merck 14,4309
pKa pKa 3.8 (Uncertain)
Storage Condition 2-8°C
Stability Stable, but light sensitive, air sensitive and hygroscopic. Incompatible with strong oxidizing agents.
Refractive Index 1.6580 (estimate)
Physical and Chemical Properties Density 1.606
melting point 220°C
Use Used as a diuretic

​Risk and Safety

Risk Codes R61 – May cause harm to the unborn child
R39/23/24/25 –
R23/24/25 – Toxic by inhalation, in contact with skin and if swallowed.
R11 – Highly Flammable
R36/37/38 – Irritating to eyes, respiratory system and skin.
Safety Description S7 – Keep container tightly closed.
S16 – Keep away from sources of ignition.
S36/37 – Wear suitable protective clothing and gloves.
S45 – In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S53 – Avoid exposure – obtain special instructions before use.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
S22 – Do not breathe dust.
S36 – Wear suitable protective clothing.
S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
UN IDs UN 1230 3/PG 2
WGK Germany 3
RTECS CB2625000
HS Code 2935904000
Toxicity LD50 orally in female, male rats: 2600, 2820 mg/kg (Goldenthal)

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