Fosinopril sodium CAS NO.88889-14-9
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Category：Active Pharmaceutical Ingredients Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
Catalog ID80017229
CAS NO.88889-14-9
Purity 95%
MDL NumberMFCD00865785
Molecular FormulaC30H45NNaO7P
Molecular Weight585.6443
Melting point: 190~192°C、
| Aspect | Details |
|---|---|
| Chemical Properties | – Molecular Formula: C30H45NNaO7P<br>- Molecular Weight: 622.67 g/mol<br>- CAS Number: 86333-80-0 |
| Mechanism of Action | Fosinopril sodium is an angiotensin-converting enzyme (ACE) inhibitor that reduces the production of angiotensin II, leading to vasodilation and reduced blood pressure. |
| Indications | – Treatment of hypertension (high blood pressure).<br>- Management of heart failure.<br>- Reduction of cardiovascular risk in patients with hypertension and left ventricular hypertrophy. |
| Dosage Forms | – Oral tablets available in 10 mg, 20 mg, and 40 mg strengths. |
| Administration | – Hypertension: Initial dose of 10 mg once daily, may be increased to 20-40 mg daily.<br>- Heart Failure: Initial dose of 5-10 mg once daily, target dose of 40 mg daily.<br>- Renal Impairment: No dose adjustment required.<br>- Hepatic Impairment: Use with caution. |
| Adverse Effects | – Common: Headache, cough, dizziness, nausea, vomiting.<br>- Serious: Angioedema (swelling of face, lips, tongue), hypotension (low blood pressure), hepatotoxicity (liver damage), hyperkalemia (high potassium levels), neutropenia (low white blood cell count). |
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