Fondaparinux Sodium intermediate N3
We are a manufacturer based in China, specializing in high-quality Fondaparinux Sodium intermediate N3 for industrial clients worldwide. Technical support and custom formulation available.
Category：Pharmaceutical Materials | Brand：MT
Introduction
Applications in Drug Developmen：
1.Mechanism of Action:
Fondaparinux Sodium is an antithrombin III (ATIII)-dependent factor Xa inhibitor.It selectively binds to ATIII, enhancing its neutralization of factor Xa by about 300 times, thereby inhibiting thrombin generation.
2.Indications:
Used for the prevention and treatment of venous thromboembolic events, such as after hip fractures or knee surgeries.
| Property | Details |
|---|---|
| Name | Fondaparinux Sodium Intermediate N3 |
| CAS No. | 114903-05-8 |
| Molecular Formula | C₈₁H₉₁N₇O₂₇ |
| Molecular Weight | 1594.64 g/mol |
| Appearance | White to off-white solid |
| Purity | ≥98% (HPLC/NMR confirmed) |
| Application | Key intermediate in synthesizing fondaparinux sodium (anticoagulant) |
| Pharmacology | Enhances ATIII inhibition of Factor Xa, disrupting coagulation cascade |
| Synthesis | Involves protection/deprotection steps, sulfation, and catalytic hydrogenation |
| QC Standards | Purity ≥98%, residual solvents <0.5%, heavy metals <10 ppm |
| Storage | -20°C, sealed, moisture-free |
| Packaging | 1g, 5g, 10g, 50g, 1kg (customizable) |
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