Folic Acid CAS No. 59-30-3
Pharmaceutical Materials 2025-03-20
Folic Acid Overview
| Category | Details | |
|---|---|---|
Basic Information |
||
| – Chemical Name | Pteroylglutamic Acid (Vitamin B9). | |
| – CAS Number | 59-30-3. | |
| – Molecular Formula | C₁₉H₁₉N₇O₆. | |
| – Molecular Weight | 441.40 g/mol. | |
| – Appearance | Yellow crystalline powder; slightly soluble in water; degrades in alkaline pH. | |
Biological Role |
||
| – Key Functions | Cofactor in DNA synthesis; supports cell division; aids methylation processes. | |
| – Deficiency Risks | Megaloblastic anemia; neural tube defects (NTDs) in pregnancy. | |
Applications |
||
| – Pharmaceutical | Prenatal vitamins; anemia treatments. | |
| – Food Fortification | Enriched cereals; dietary supplements. | |
| – Agricultural | Livestock feed additive. | |
Safety & Storage |
||
| – Daily Intake Limits | Adults: 400–800 μg (varies by region); avoid overdose (>1,000 μg/day). | |
| – Storage Conditions | Cool (<25°C), dry, light-protected; shelf life 24 months. | |
Regulatory Compliance |
USP/NF, EP, JP; GRAS status for food use. |
Summary:
Folic acid is a water-soluble vitamin essential for DNA replication and cellular growth. It acts as a coenzyme in nucleotide biosynthesis and plays a critical role in preventing birth defects during early pregnancy. Commercially, it is used in prenatal supplements, fortified foods, and animal feed. Stability is compromised in moisture and light, necessitating controlled storage. Regulatory bodies set strict guidelines for its use in healthcare and food industries.
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