
Fluralaner
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Category:Active Pharmaceutical Ingredients Own Brand:MT /MOQ:100KG /From China/ B2B only.
Introduction
Sugammadex sodium 4-(5-(3,5-Dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-2-methyl-N-(2-oxo-2-(2,2,2-trifluoroethylamino)ethyl)benzamide 4-[5-(3,5-Dichlorophenyl)-5-(Trifluoromethyl)-4H-1,2-Oxazol-3-Yl]-2-Methyl-N-[2-Oxo-2-(2,2,2-Trifluoroethylamino)Ethyl]Benzamide
Catalog ID101054
CAS NO.864731-61-3
Purity 95% MDL
NumberMFCD30533410
EINEC Molecular Formula C22H17Cl2F6N3O3
Molecular Weight 556.288
| Category | Content |
|---|---|
| Generic Name | Fluralaner |
| Chemical Formula | C22H17Cl2F6N3O3 |
| Mechanism of Action | Fluralaner is a GABA (γ-aminobutyric acid) and L-glutamate gated chloride channel inhibitor. It blocks these channels in the nervous system of arthropods, leading to hyperexcitation and death. |
| Indications | Used for the treatment and prevention of flea and tick infestations in dogs and cats. It is also effective against mites and may be used to control other ectoparasites. |
| Dosage Forms | Oral tablets and chewables |
| Pharmacokinetics | Fluralaner is rapidly absorbed after oral administration, reaching maximum plasma concentrations within 1 day. It has a long half-life (approximately 12 days) and is primarily excreted unchanged in feces. |
| Side Effects | Generally well-tolerated. Possible side effects include vomiting, diarrhea, decreased appetite, or flaky skin. |
| Developer | Merck Animal Health (known as MSD Animal Health outside the US and Canada) |
| Approval Date | Approved by the FDA in May 2014, the EU in February 2014, and Australia in January 2015. |
| Brand Name | Bravecto |
| Duration of Effect | A single dose provides at least 12 weeks of protection against fleas and ticks. |
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