Fluralaner

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Category:Active Pharmaceutical Ingredients   Own Brand:MT  /MOQ:100KG  /From China/  B2B only.

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Introduction

Sugammadex sodium 4-(5-(3,5-Dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-2-methyl-N-(2-oxo-2-(2,2,2-trifluoroethylamino)ethyl)benzamide 4-[5-(3,5-Dichlorophenyl)-5-(Trifluoromethyl)-4H-1,2-Oxazol-3-Yl]-2-Methyl-N-[2-Oxo-2-(2,2,2-Trifluoroethylamino)Ethyl]Benzamide

Catalog ID101054

CAS NO.864731-61-3

Purity 95% MDL

NumberMFCD30533410

EINEC Molecular Formula C22H17Cl2F6N3O3

Molecular Weight 556.288

Category Content
Generic Name Fluralaner
Chemical Formula C22H17Cl2F6N3O3
Mechanism of Action Fluralaner is a GABA (γ-aminobutyric acid) and L-glutamate gated chloride channel inhibitor. It blocks these channels in the nervous system of arthropods, leading to hyperexcitation and death.
Indications Used for the treatment and prevention of flea and tick infestations in dogs and cats. It is also effective against mites and may be used to control other ectoparasites.
Dosage Forms Oral tablets and chewables
Pharmacokinetics Fluralaner is rapidly absorbed after oral administration, reaching maximum plasma concentrations within 1 day. It has a long half-life (approximately 12 days) and is primarily excreted unchanged in feces.
Side Effects Generally well-tolerated. Possible side effects include vomiting, diarrhea, decreased appetite, or flaky skin.
Developer Merck Animal Health (known as MSD Animal Health outside the US and Canada)
Approval Date Approved by the FDA in May 2014, the EU in February 2014, and Australia in January 2015.
Brand Name Bravecto
Duration of Effect A single dose provides at least 12 weeks of protection against fleas and ticks.

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