Fludarabine

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Category:Chemical Intermediates   Own Brand:MT  /MOQ:100KG  /From China/  B2B only.

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Introduction

Molecular Formula: C10H12FN5O4

Molecular Weight: 285.23

CAS No.: 21679-14-1

Description It is a white or almost white crystalline powder. It is soluble in water, insoluble in organic solvents.

Name Fludarabine
Synonyms f-ara-a
NSC 118218
Fludarabine
NSC 118218H
Fludarabine base
Fludarabine(base)
2-Fluoroadeninearabinoside
9-beta-D-Arabinofuranosyl-2-fluoroadenine
9-bata-D-Arabinofuranosyl-2-fluoroadenine
9-beta-d-arabinofuranosyl-2-fluoro-adenin
2-Fluoroadenine-9-bata-D-arabinofuranoside
6-AMINO-9 BETA-D-ARABINOFURANOSYLFLUOROPURINE
9–D-Arabinofuranosyl-2-fluoro-9H-purin-6-amine
9-beta-d-arabinofuranosyl-2-fluoro-9h-purin-6-amin
9-(beta-D-arabinofuranosyl)-2-fluoro-9H-purin-6-amine

Physico-chemical Properties

Molecular Formula C10H12FN5O4
Molar Mass 285.23
Density 2.17±0.1 g/cm3(Predicted)
Melting Point 265-268°C
Boling Point 747.3±70.0 °C(Predicted)
Specific Rotation(α) D25 +17 ±2.5° (c = 0.1 in ethanol)
Flash Point 405.8°C
Water Solubility Soluble in DMF, DMSO, methanol or ethanol. Sparingly soluble in water
Solubility Soluble in (<1 mg/mL,25°C), DMSO (57 mg/mL,25°C), and ethanol (<1 mg/mL,25°C).
Vapor Presure 1.86E-23mmHg at 25°C
Appearance White or white-like crystalline powder
Color White to Pale Yellow
Merck 13,4152
BRN 1225932
pKa 13.05±0.70(Predicted)
Storage Condition 2-8°C
Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Refractive Index 1.876
MDL MFCD00132942
Physical and Chemical Properties Crystallization from ethanol-water, melting point 260 °c. [Α] D23 17 ° ± 2.5 °(C = 0.1, ethanol). UV absorption maximum (Ph 1, pH 7, ph 13):262,261,262nm(ε 13200,14800,15000). Difficult to dissolve in water and organic solvents. Fiudarabine 5 ‘-monophosphorate: C10Hl3FN5O7P. [75607-67-9]. Soluble in water.
Use This product is for scientific research only and shall not be used for other purposes.
Target STAT1(Vascular smooth muscle cells)

​ Risk and Safety

Hazard Symbols Xn – Harmful
Risk Codes R23/24/25 – Toxic by inhalation, in contact with skin and if swallowed.
R36/37/38 – Irritating to eyes, respiratory system and skin.
R39/23/24/25 –
R39 – Danger of very serious irreversible effects
R22 – Harmful if swallowed
Safety Description S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37 – Wear suitable protective clothing and gloves.
S45 – In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36 – Wear suitable protective clothing.
WGK Germany 3
RTECS AU6207000
FLUKA BRAND F CODES 10
HS Code 29349990

,Disclaimer: The above content is for reference and communication only among industry insiders, and does not guarantee its accuracy or completeness. According to relevant laws and regulations and the regulations of this website, units or individuals who purchase related items should obtain valid qualifications and qualification conditions.

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