FidaxoMicin CAS NO.:873857-62-6
Active Pharmaceutical Ingredients 2025-03-11
CAS NO.:873857-62-6
Molecular formula:C52H74Cl2O18
Molecular weight:1058.04
Standard：enterprise standard
Content：≥98.0%
Packaging:100G/BAG
Use to:macrolide antibiotics
Fidaxomicin: A Selective Antibacterial Agent
Fidaxomicin is a narrow – spectrum macrocyclic antibiotic primarily used for treating Clostridioides difficile infections (CDI).
1. Basic Characteristics
| Aspect | Details |
|---|---|
| Classification | Macrocyclic antibiotic (structurally related to rifamycins) |
| Target | Bacterial RNA polymerase |
| Spectrum | Primarily effective against Gram – positive bacteria, especially Clostridioides difficile |
| Formulation | Oral tablets (120 mg per dose) |
2. Mechanism of Action
| Process | Explanation |
|---|---|
| RNA Polymerase Inhibition | Binds to the β – subunit of bacterial RNA polymerase, blocking transcription initiation |
| Selective Activity | Preferentially targets C. difficile while preserving gut microbiota |
| Bactericidal Effect | Disrupts protein synthesis and cell wall integrity in susceptible bacteria |
