Fenpyroximate CAS NO.134098-61-6
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Category：Active Pharmaceutical Ingredients Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
Catalog ID80017723
CAS NO.134098-61-6
Purity 96%
MDL NumberMFCD00274596
Molecular Formula C24H27N3O4
Molecular Weight 421.4889
Melting point: 101.1~102.4°C
| Aspect | Details |
|---|---|
| Mechanism of Action | Fenpyroximate is a selective mitochondrial complex I inhibitor. Its high specificity as a miticide is primarily due to differential rates of metabolic detoxification, particularly through removal of the t-Bu group yielding the free carboxylic acid analog, which is inactive as a complex I inhibitor. |
| Pharmacokinetics | – Absorption: Well absorbed after oral administration in rats. Poorly absorbed through the skin.<br>- Distribution: No parent compound found in urine; metabolites represent 0-11% of the administered dose.<br>- Metabolism: Extensively metabolized in rats via hydrolysis, oxidation, hydroxylation, demethylation, and conjugation.<br>- Excretion: Predominantly via the biliary route, with lesser amounts in urine and feces. |
| Ecotoxicity | – Aquatic Toxicity: Highly toxic to marine flounder and its gill cell line (FG). The liver and gills are the major target organs, with the gills being particularly susceptible.<br>- Environmental Fate: Persistent in soil and water; volatilization from water surfaces is significant but attenuated by adsorption to suspended solids. |
| Environmental Exposure | – Release: Direct release into the environment through agricultural use.<br>- Occupational Exposure: Potential inhalation and dermal contact during production and use. |
| Dietary Intake | Residues can be detected in agricultural products; specific dietary intake levels depend on application rates and environmental conditions. |
| Storage and Handling | Store in a cool, dry place, protected from light and moisture. Handle with care to avoid inhalation and dermal contact. |
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