Fasudil hydrochloride
We are a manufacturer based in China, specializing in high-quality Fasudil hydrochloride for industrial clients worldwide. Technical support and custom formulation available.
Category：Active Pharmaceutical Ingredients | Brand：MT
Factory Direct
7-30 Days Lead Time
MOQ: 100KG
Global Export
Introduction
Catalog ID80071744
CAS NO.105628-07-7
Purity 98+%
MDL NumberMFCD00943198
Molecular Formula C14H17N3O2S.HCl
Molecular Weight 327.83
Melting point: 208 – 215°C
| Category | Content |
|---|---|
| Generic Name | Fasudil Hydrochloride Monohydrate |
| Chemical Formula | C14H18ClN3O2S |
| CAS Number | 105628-07-7 |
| Mechanism of Action | Fasudil is a non-specific RhoA/ROCK inhibitor with Ki values of 0.33 μM for ROCK1 and 0.158 μM for ROCK2. It also inhibits protein kinases (e.g., PKA, PKC) and acts as a Ca²⁺ channel antagonist. |
| Indications | – Treatment of cerebral vasospasm.<br>- Investigated for conditions like cardiovascular disease and liver fibrosis. |
| Common Side Effects | – Headache.<br>- Hypotension.<br>- Nausea.<br>- Injection site reactions. |
| Less Common Side Effects | – Tachycardia.<br>- Gastrointestinal disturbances.<br>- Allergic reactions.<br>- Liver function alterations.<br>- Renal impairment.<br>- Central nervous system effects. |
| Storage | Store at room temperature, protect from moisture. |
| Developer | Originally developed by Astellas Pharma. |
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