Fasudil hydrochloride
We are a manufacturer based in China. We specialize in providing high-quality Fasudil hydrochloride for industrial clients across various sectors. Whether you need chemicals consultation or technical support, our team is here to help.
Category：Active Pharmaceutical Ingredients Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
Catalog ID80071744
CAS NO.105628-07-7
Purity 98+%
MDL NumberMFCD00943198
Molecular Formula C14H17N3O2S.HCl
Molecular Weight 327.83
Melting point: 208 – 215°C
| Category | Content |
|---|---|
| Generic Name | Fasudil Hydrochloride Monohydrate |
| Chemical Formula | C14H18ClN3O2S |
| CAS Number | 105628-07-7 |
| Mechanism of Action | Fasudil is a non-specific RhoA/ROCK inhibitor with Ki values of 0.33 μM for ROCK1 and 0.158 μM for ROCK2. It also inhibits protein kinases (e.g., PKA, PKC) and acts as a Ca²⁺ channel antagonist. |
| Indications | – Treatment of cerebral vasospasm.<br>- Investigated for conditions like cardiovascular disease and liver fibrosis. |
| Common Side Effects | – Headache.<br>- Hypotension.<br>- Nausea.<br>- Injection site reactions. |
| Less Common Side Effects | – Tachycardia.<br>- Gastrointestinal disturbances.<br>- Allergic reactions.<br>- Liver function alterations.<br>- Renal impairment.<br>- Central nervous system effects. |
| Storage | Store at room temperature, protect from moisture. |
| Developer | Originally developed by Astellas Pharma. |
Disclaimer: The above content is for reference and communication only among industry insiders, and does not guarantee its accuracy or completeness. According to relevant laws and regulations and the regulations of this website, units or individuals who purchase related items should obtain valid qualifications and qualification conditions.
If you're ready to take the next step, Leave your message below and we’ll reply soon. 20+ years of chemical manufacturing & export experience, a partner you can trust.
Inquiry
Factory & Shipment
