Faropenem sodium CAS NO.122547-49-3
Active Pharmaceutical Ingredients 2025-03-03
Catalog ID80017862
CAS NO.122547-49-3
Purity 98%
MDL NumberMFCD07357271
Molecular Formula C12H14NNaO5S
Molecular Weight 307.298
| Category | Details |
|---|---|
| Chemical Properties | Molecular formula: C12H14NNaO5S<br> Molecular weight: 326.31 g/mol |
| Mechanism of Action | Faropenem sodium is a β-lactam antibiotic with a broad spectrum of activity against both Gram-positive and Gram-negative bacteria. It inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), leading to cell lysis and death. It is stable against most β-lactamases, including extended-spectrum β-lactamases (ESBLs) produced by Enterobacteriaceae. |
| Therapeutic Uses | Pediatric Infections: Used to treat a wide range of infections in children, including pneumonia, bronchitis, pharyngitis, tonsillitis, otitis media, sinusitis, urinary tract infections, skin infections, and dental infections.<br> Adult Infections: Also used in adults for similar infections. |
| Formulations | Available as dry syrup for oral suspension. |
| Dosage | Children: Typically 5–10 mg/kg orally, 3 times daily. The dose can be adjusted based on the severity of the infection.<br> Adults: Dosing varies based on the type and severity of the infection. |
| Pharmacokinetics | Absorption: Rapidly absorbed after oral administration, with peak plasma concentrations reached within 1 hour.<br> Distribution: Widely distributed in tissues, including sputum, skin, and urine.<br> Metabolism: Partially metabolized by renal dipeptidase-1 (DHP-1) in the kidneys.<br> Excretion: Primarily excreted in urine. |
| Safety and Side Effects | Generally well-tolerated with a low incidence of adverse effects such as diarrhea, nausea, or vomiting. No significant cardiotoxicity or seizure risk reported. |
| Storage Conditions | Store at room temperature, protected from light and moisture |
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