Exemestane
Active Pharmaceutical Ingredients 2025-03-03
Catalog ID80017975
CAS NO.107868-30-4
Purity 99%
MDL NumberMFCD00866994
Molecular FormulaC20H24O2
Molecular Weight296.4034
Melting point: 189~190°C
| Category | Details |
|---|---|
| Chemical Properties | Molecular formula: C20H24O2<br> Molecular weight: 296.41 g/mol |
| Physical Properties | Appearance: White to off-white powder<br> Solubility: Soluble in DMSO (≥20 mg/mL) |
| Mechanism of Action | Irreversible aromatase inhibitor. Binds to and inactivates the aromatase enzyme, reducing estrogen levels in postmenopausal women. |
| Therapeutic Uses | Early Breast Cancer: Used in postmenopausal women after 2–3 years of tamoxifen treatment.<br> Advanced Breast Cancer: Used in postmenopausal women whose cancer has progressed after tamoxifen. |
| Dosage | 25 mg orally once daily, preferably with food. |
| Side Effects | Common: Hot flashes, joint pain, headache, nausea, insomnia.<br> Serious: Severe allergic reactions, decreased bone density. |
| Storage Conditions | Store at room temperature (15–30°C), protect from moisture and light. |
| Brand Name | Aromasin |
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