Ethyl 4,4-difluoro-3-oxobutanoate
Pharmaceutical Materials 2025-03-02
CAS Number: 352-24-9
Molecular Formula: C6H8F2O3
Molecular Weight: 166.12 g/mol
Appearance: Colorless transparent liquid
Density: Approximately 1.191 g/cm3
Boiling Point: 170.1°C at 760 mmHg
Usage: It is used as a chemical intermediate.
| Property | Details |
|---|---|
| Chemical Name | Ethyl 4.4-difluoro-3-oxobutanoate |
| Alternative Names | 4.4-Difluoroacetoacetic Acid Ethyl Ester; Ethyl 4.4-difluoroacetoacetate; 4.4-Difluoro-3-oxobutyric Acid Ethyl Ester; 4.4-Difluoroacetylacetic Acid Ethyl Ester |
| CAS Number | 352-24-9 |
| Molecular Formula | C6H8F2O3 |
| Molecular Weight | 166.1227 g/mol |
| Density | 1.191 g/cm³ |
| Boiling Point | 170.1°C at 760 mmHg |
| Flash Point | 55.7°C |
| Vapor Pressure | 1.49 mmHg at 25°C |
| EINECS Number | 206-519-0 |
| Application | Important intermediate in pesticides and pharmaceuticals, used in the preparation of Sedaxane, Solatenol (Benzovindiflupyr), Isopyrazam, Fluxapyroxad, and Bixafen. |
| Synthesis Route | Prepared through reactions involving ethanol, sodium ethoxide, ethyl acetate, and difluoroacetic acid ethyl ester, followed by purification steps. |
| Physical State | Liquid |
| Hazard Information | Flammable, keep away from heat and open flames. Handle with appropriate personal protective equipment. |
Disclaimer: The above content is for reference and communication only among industry insiders, and does not guarantee its accuracy or completeness. According to relevant laws and regulations and the regulations of this website, units or individuals who purchase related items should obtain valid qualifications and qualification conditions.
