Ethyl 4-hydroxyphenylacetate
Pharmaceutical Materials 2025-03-02
CAS Number: 17138-28-2
Molecular Formula: C10H12O3
Molecular Weight: 180.20 g/mol
Appearance: Colorless to light yellow liquid (or white crystalline solid according to some sources)
Usage: Mainly used as a pharmaceutical intermediate.
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| Attribute | Details |
|---|---|
| Chemical Name | Ethyl 4-hydroxyphenylacetate |
| Synonyms | 4-Hydroxyphenylacetic acid ethyl ester; p-Hydroxyphenylacetic acid ethyl ester; Ethyl p-hydroxyphenylacetate |
| CAS Number | 17138-28-2 |
| EINECS Number | 241-197-5 |
| Molecular Formula | C10H12O3 |
| Molecular Weight | 180.20 g/mol |
| Chemical Structure | Features an aromatic ring with a hydroxyl group (-OH) at the 4-position, an ethyl ester group (-OOCH2CH3) attached to the carbon adjacent to the hydroxyl group on the aromatic ring. |
| Physical State | A light yellow to colorless liquid. |
| Physical Properties | – Melting Point: 36-38°C. |
| – Boiling Point (at 20 mmHg): 187-189°C. | |
| – Density and other properties may vary and are not definitively listed. | |
| Chemical Properties | Stable under normal conditions. Avoid contact with oxidizing agents. |
| Applications | Primarily used as a pharmaceutical intermediate. |
| Biological Activity | Acts as a selective inhibitor of monoamine oxidase A (MAO-A). |
| Storage Conditions | Store in a cool, dry place, away from direct sunlight and oxidizing agents, ensuring the container is tightly sealed. |
| Safety Information | Handle with appropriate personal protective equipment, such as gloves and protective eyewear. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical attention if necessary. Follow local regulations for the disposal and handling of chemicals. |


