Ethyl 2-(3-formyl-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate
Category：Pharmaceutical Materials
Introduction
Molecular Formula: C18H21NO4S Molecular Weight: 347.43 CAS Registry Number: 161798-03-4 Density: 1.183
Name: Ethyl 2-(3-formyl-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate
CAS: 161798-03-4
Appearance: yellowish to white powder
Assay: ≥99%
Capacity: 100mt/year
Min.package: 1gram
Application: Febuxostat intermediate
Standard: enterprise export
2- (3-aldehyde-4-isobutyloxyphenyl) -4-methylthiazole-5-carboxylic acid ethyl ester is an organic compound, whose molecular structure includes a thiazole ring and a benzene ring. Here are some properties, uses, preparation methods, and safety information of the compound:
nature:
-Appearance: White to light yellow powder or crystal.
-Solubility: soluble in some organic solvents, such as dimethyl sulfoxide and alcohols.
Purpose:
Manufacturing method:
-2- (3-aldehyde-4-isobutyloxyphenyl) -4-methylthiazole-5-carboxylic acid ethyl ester can be prepared by reacting 3-amino-4-isobutyloxyphenyl aldehyde with 2-amino-4-methylthiazole-5-carboxylic acid ethyl ester.
Security information:
-The safety information of this compound is rarely reported, and appropriate laboratory safety measures need to be taken during operation.
-This compound may have irritant effects on the skin and eyes, and care should be taken to avoid contact with the skin and eyes during operation.
-Before use, please read and follow the relevant safety operation guidelines and personal protective measures.
| Name | Ethyl 2-(3-Formyl-4-isobutoxyphenyl)-4-Methylthiazole-5-Carboxylate |
| Synonyms | 2-(3-forMyl Febuxostat-24 Febuxostat Impurity 2 Febuxostat Impurity G Ethyl 2-(3-formyl-4-isobutoxyphenyl)-4-methylthiazole- Ethyl 2-(3-Formyl-4-isobutoxyphenyl)-4-Methylthiazole-5-Carboxylate Ethyl 2-(3-formyl-4-isobutoxyphenyl)-4-methyl-5- Thiazolecarboxylate Ethyl 2-(3-formyl-4-iso butoxyphenyl)-4-methylthiazole-5-carboxylate Ethyl-2-(3-Formyl-4-isobutoxy phenyl)-4-methyl-1,3-thiazole-5-carboxylate ethyl-2-[3-forMyl-4-(2-Methylpropoxy)phenyl]-4-Methyl-5-thiazolecarboxylate Ethyl-2-[3-formyl-4-(2-methylpropoxy)phenyl]-4-Methyl-5-Thiazolecarboxylate ethyl 2-[3-formyl-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylate 2-[3-Formyl-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic acid ethyl ester 5-Thiazolecarboxylicacid, 2-[3-forMyl-4-(2-Methylpropoxy)phenyl]-4-Methyl-, ethyl ester |
| CAS | 161798-03-4 |
| EINECS | 700-743-7 |
| InChI | InChI=1/C18H21NO4S/c1-5-22-18(21)16-12(4)19-17(24-16)13-6-7-15(14(8-13)9-20)23-10-11(2)3/h6-9,11H,5,10H2,1-4H3 |
| Molecular Formula | C18H21NO4S |
| Molar Mass | 347.43 |
| Density | 1.183 |
| Melting Point | 158-160°C |
| Boling Point | 495.9±55.0 °C(Predicted) |
| Flash Point | 253.7°C |
| Solubility | Chloroform (Slightly), Methanol (Slightly, Sonicated) |
| Vapor Presure | 5.68E-10mmHg at 25°C |
| Appearance | Solid |
| Color | Pale Yellow |
| pKa | 1.39±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.566 |
| Physical and Chemical Properties | Appearance: off-white crystalline powder |
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