Etamsylate
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Category：Active Pharmaceutical Ingredients Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
Catalog ID80017978
CAS NO.2624-44-4
Purity 96%
MDL NumberMFCD00867499
Molecular Formula C10H17NO5S
Molecular Weight 263.3107
Melting point: 127~131°C
| Category | Details |
|---|---|
| Chemical Properties | Molecular formula: C10H17NO5S<br> Molecular weight: 263.31 g/mol |
| Physical Properties | Appearance: White crystalline powder<br> Melting point: 124–129°C |
| Mechanism of Action | Hemostatic Agent: Enhances platelet adhesion and aggregation, promotes thromboplastin formation, and decreases prostacyclin (PGI2) synthesis.<br> Angioprotective: Increases capillary resistance and stabilizes capillary membranes.<br> Prostaglandin Inhibition: Reduces the biosynthesis and action of prostaglandins that cause platelet disaggregation and increased capillary permeability. |
| Therapeutic Uses | Bleeding Disorders: Used for prophylaxis and control of hemorrhages from small blood vessels, including menorrhagia, metrorrhagia, hematemesis, melena, hematuria, and epistaxis.<br> Surgical Bleeding: Prevents excessive bleeding during and after surgery.<br> Neonatal Intraventricular Hemorrhage: Used in premature infants to prevent periventricular hemorrhage. |
| Formulations | Available as tablets, injections, and solutions for intravenous or intramuscular use. |
| Dosage | Adults: 0.5–1.0 g orally or by injection, 3 times daily.<br> Children: 10 mg/kg orally or by injection, 3 times daily.<br> Preoperative Use: 0.25–0.5 g intravenously or intramuscularly 15–30 minutes before surgery. |
| Storage Conditions | Store at room temperature, protect from moisture and light. |
| Safety Information | Side Effects: Rarely causes mild gastrointestinal discomfort.<br> Contraindications: Avoid in patients with hypersensitivity to etamsylate.<br> Drug Interactions: Do not mix with aminocaproic acid for injection to avoid toxicity.<br> Pregnancy and Lactation: Use with caution; benefits should outweigh potential risks |
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