Erythromycin estolate CAS NO.3521-62-8
Active Pharmaceutical Ingredients 2025-03-03
Catalog ID80017794
CAS NO.3521-62-8
Purity 98%
MDL NumberMFCD00084691
EINEC222-532-4
Molecular formula C40H71NO14.C12H26SO4
Molecular weight 1056.3875
Melting point: 135~140℃
| Aspect | Details |
|---|---|
| Mechanism of Action | Erythromycin estolate is a prodrug that is converted into its active form, erythromycin, in the body. It binds to the 50S ribosomal subunit of bacterial cells, inhibiting protein synthesis and thereby preventing bacterial growth. |
| Storage Conditions | Store in a dry, cool, and well-ventilated place. Keep tightly closed and protect from light. |
| Special Considerations | – Hepatotoxicity: Prolonged use may cause liver toxicity.<br>- Drug Interactions: Erythromycin estolate inhibits cytochrome P450 enzymes (CYP3A4), which can alter the metabolism of other drugs, potentially leading to significant interactions.<br>- Allergic Reactions: May cause allergic skin reactions or respiratory sensitization.<br>- Gastrointestinal Effects: Can cause abdominal cramps and diarrhea due to its motilin agonist activity |
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