Erdosteine
Active Pharmaceutical Ingredients 2025-03-03
Catalog ID80019645
CAS NO.84611-23-4
Purity 98%
MDL NumberMFCD00867664
Molecular FormulaC8H11NO4S2
Molecular Weight249.3072
Melting point: 156~158°C
| Category | Information |
|---|---|
| Chemical Properties | – Molecular Formula: C₈H₁₁NO₄S₂ <br>- Molecular Weight: 253.31 g/mol |
| Physical Properties | – Appearance: White crystalline powder <br>- Melting Point: Not explicitly mentioned |
| Mechanism of Action | – Erdosteine is a thiol-based mucolytic agent that reduces mucus viscosity and enhances mucociliary clearance.<br>- It also acts as an antioxidant and anti-inflammatory agent, reducing oxidative stress and inflammation.<br>- Erdosteine has antibacterial properties, reducing bacterial adhesion and improving antibiotic efficacy. |
| Clinical Uses | – Respiratory Diseases: Used for the management of chronic obstructive pulmonary disease (COPD) and chronic bronchitis.<br>- Acute and Chronic Conditions: Effective in reducing the frequency and severity of exacerbations, improving symptoms such as cough and sputum viscosity.<br>- Antibiotic Synergy: Enhances the effectiveness of antibiotics like amoxicillin in treating respiratory infections. |
| Dosage Forms | – Oral Tablets: Typically administered at 300 mg twice daily. |
| Adverse Effects | – Common side effects include gastrointestinal disturbances, which are generally mild. |
| Storage Conditions | Store in a cool, dry place, protected from moisture. |
| Synonyms | – Esteclin <br>- RV-144 <br>- Vectrine |
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