Active Pharmaceutical Ingredients

Catalog ID80071741

CAS NO.107007-95-4

Purity 98%

MDL NumberMFCD00872014

Molecular FormulaC17H22N4O

Molecular Weight298.3828

Melting point: 224~227°C

Category	Content
Name	Endo-N-(9-methyl-9-azabicyclo[3.3.1]non-3-yl)-1H-indazole-3-carboxamide
Chemical Formula	C19H25N3O2
CAS Number	156455-60-3
Molecular Weight	327.42 g/mol
Mechanism of Action	This compound is a selective inhibitor of the enzyme 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), which converts cortisone to cortisol. By inhibiting this enzyme, it reduces cortisol levels and has potential therapeutic applications in metabolic disorders.
Applications	– Research: Used in studies related to glucocorticoid metabolism and metabolic syndrome.<br>- Medicine: Investigated for potential use in treating type 2 diabetes, obesity, and other metabolic disorders.
Physical Properties	– Appearance: White to off-white solid.<br>- Solubility: Soluble in DMSO (10 mM).<br>- Storage: Store at -20°C for 3 years; in solvent at -80°C for 1 year.
Safety Information	– Handle with care to avoid contact with skin and eyes.<br>- Store in a cool, dry place.
Developer	Originally synthesized and studied by various research groups

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