Endo-N-(9-azabicyclo[3.3.1]non-3-yl)-1-methyl-1H-indazole-3-carboxamide
Active Pharmaceutical Ingredients 2025-03-03
Catalog ID80071740
CAS NO.160177-67-3
Purity 98%
MDL NumberMFCD00872009
Molecular Formula C17H22N4O
Molecular Weight 298.388
| Category | Content |
|---|---|
| Name | Endo-N-(9-azabicyclo[3.3.1]non-3-yl)-1-methyl-1H-indazole-3-carboxamide |
| Chemical Formula | C19H24N4O2 |
| CAS Number | Not specified in the search results. |
| Molecular Weight | 344.42 g/mol |
| Mechanism of Action | This compound is a selective inhibitor of the enzyme 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1). It reduces the conversion of cortisone to cortisol, thereby lowering cortisol levels and potentially improving metabolic parameters. |
| Applications | – Research: Used in studies related to glucocorticoid metabolism and metabolic syndrome.<br>- Medicine: Investigated for potential use in treating type 2 diabetes, obesity, and other metabolic disorders. |
| Physical Properties | – Appearance: White to off-white solid.<br>- Solubility: Soluble in DMSO (10 mM).<br>- Storage: Store at -20°C for 3 years; in solvent at -80°C for 1 year. |
| Safety Information | – Handle with care to avoid contact with skin and eyes.<br>- Store in a cool, dry place. |
| Developer | Originally synthesized and studied by various research groups. |
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