Active Pharmaceutical Ingredients

Catalog ID80071740

CAS NO.160177-67-3

Purity 98%

MDL NumberMFCD00872009

Molecular Formula C17H22N4O

Molecular Weight 298.388

Category	Content
Name	Endo-N-(9-azabicyclo[3.3.1]non-3-yl)-1-methyl-1H-indazole-3-carboxamide
Chemical Formula	C19H24N4O2
CAS Number	Not specified in the search results.
Molecular Weight	344.42 g/mol
Mechanism of Action	This compound is a selective inhibitor of the enzyme 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1). It reduces the conversion of cortisone to cortisol, thereby lowering cortisol levels and potentially improving metabolic parameters.
Applications	– Research: Used in studies related to glucocorticoid metabolism and metabolic syndrome.<br>- Medicine: Investigated for potential use in treating type 2 diabetes, obesity, and other metabolic disorders.
Physical Properties	– Appearance: White to off-white solid.<br>- Solubility: Soluble in DMSO (10 mM).<br>- Storage: Store at -20°C for 3 years; in solvent at -80°C for 1 year.
Safety Information	– Handle with care to avoid contact with skin and eyes.<br>- Store in a cool, dry place.
Developer	Originally synthesized and studied by various research groups.

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