Active Pharmaceutical Ingredients

Molecular Formula: C18H15Cl3N2O,HNO3

Molecular Weight: 444.7

CAS No.: 68797-31-9

Econazole nitrate is a pyrrole antifungal drug and a dechlorinated derivative of miconazole. It has antibacterial activity against Candida, chromomycetes, coccidiospores, histoplasm, Sporothrix, and Trichophyton.

Description

The product is white or yellowish crystalline or crystalline powder; Odorless. The product is easily soluble in methanol, slightly soluble in chloroform and very slightly soluble in water. Melting point the melting point of the product (Appendix VI C) is 163 ~ 167 ℃, and it decomposes at the same time when melting.

Application

For the treatment of cutaneous candidiasis; It can also be used to treat tinea corporis, tinea manus, tinea cruris, tinea pedis, tinea versicolor, etc.

Packing and Storage

Preserve in well-closed containers, protected from light.

Minimum Order

One package

Title	Content
Introduction	Econazole Nitrate is an antifungal medication used to treat various fungal skin infections. It is available in topical forms such as creams and foams.
Mechanism of Action	Econazole Nitrate is an imidazole derivative that inhibits the biosynthesis of ergosterol, a key component of fungal cell membranes. This disruption prevents fungal growth and kills the fungus.
Medical Uses	– Athlete’s Foot (Tinea Pedis)<br>- Jock Itch (Tinea Cruris)<br>- Ringworm (Tinea Corporis)<br>- Cutaneous Candidiasis<br>- Tinea Versicolor<br>- Interdigital Tinea Pedis (Foam Formulation)
Dosage Forms	– Topical Cream: Applied once or twice daily depending on the condition.<br>- Topical Foam: Applied once daily for conditions like interdigital tinea pedis.
Common Side Effects	– Skin Reactions: Burning, itching, stinging, redness, and dryness at the application site.<br>- Allergic Reactions: Skin rash, swelling, or irritation.
Serious Side Effects	– Long-term Use: Potential for skin atrophy, telangiectasia, and secondary infections.<br>- Systemic Effects: Rare but may include headache or nausea.
Precautions	– Avoid contact with eyes, nose, mouth, and vagina.<br>- Do not use on viral infections like herpes or chickenpox.<br>- Use only as directed by your doctor to avoid irritation or resistance.
Storage Conditions	Store at room temperature (20°C to 25°C). Do not refrigerate or freeze the foam formulation.

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