Duloxetine hydrochloride CAS 136434-34-9
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Category：Active Pharmaceutical Ingredients Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
Chemical Name:Duloxetine hydrochloride
CAS No.: 136434-34-9
Assay: ≥ 99.0%
Appearance：white powder
Duloxetine hydrochloride More Details：
Appearance white powder
Assay% 99%
molecular formula C18H20ClNOS
molecular weight 333.88
melting point 118-122°C
Flash point 9°C
Duloxetine hydrochlorideUsage：
For the treatment of depression and tension urinary incontinence.
Duloxetine hydrochloridePackaging and Shipping：
25kg/ drum，25kg/bag or as per buyer requirement.
Duloxetine hydrochlorideStorage：
Store in a ventilated low-temperature dry warehouse;Store separately with oxidants, acids and alkali.
| Item | Content |
|---|---|
| Introduction | Duloxetine hydrochloride (CAS No.: 136434-34-9) is a selective serotonin and norepinephrine reuptake inhibitor (SNRI) used primarily to treat depression, anxiety disorders, and neuropathic pain. It is marketed under the brand name Cymbalta. |
| Chemical Properties | – Molecular Formula: C₁₈H₂₀ClNOS<br>- Molecular Weight: 333.9 g/mol<br>- Appearance: White to off-white powder. |
| Mechanism of Action | Duloxetine hydrochloride increases the levels of serotonin and norepinephrine in the brain by inhibiting their reuptake, thereby improving mood and reducing pain. |
| Medical Uses | – Depression: Used to treat major depressive disorder.<br>- Anxiety Disorders: Effective for generalized anxiety disorder and social anxiety disorder.<br>- Neuropathic Pain: Used to treat diabetic peripheral neuropathic pain and fibromyalgia. |
| Dosage Forms | – Capsules: Available in various strengths for oral administration.<br>- Delayed-Release Tablets: For extended release and better absorption. |
| Storage Conditions | Store at room temperature (15°C to 30°C), protect from moisture and light. |
| Safety Information | – Toxicity: Moderate toxicity by ingestion.<br>- Handling: Avoid contact with eyes and skin; wear appropriate protective equipment.<br>- Contraindications: Avoid in patients with uncontrolled narrow-angle glaucoma. |
| Regulatory Status | – USP: Complies with USP standards.<br>- EP: European Pharmacopoeia reference standard. |
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