Active Pharmaceutical Ingredients

Chemical Name:Duloxetine hydrochloride

CAS No.: 136434-34-9

Assay: ≥ 99.0%

Appearance：white powder

Duloxetine hydrochloride More Details：

Appearance white powder

Assay% 99%

molecular formula C18H20ClNOS

molecular weight 333.88

melting point 118-122°C

Flash point 9°C

Duloxetine hydrochlorideUsage：

For the treatment of depression and tension urinary incontinence.

Duloxetine hydrochloridePackaging and Shipping：

25kg/ drum，25kg/bag or as per buyer requirement.

Duloxetine hydrochlorideStorage：

Store in a ventilated low-temperature dry warehouse;Store separately with oxidants, acids and alkali.

Item	Content
Introduction	Duloxetine hydrochloride (CAS No.: 136434-34-9) is a selective serotonin and norepinephrine reuptake inhibitor (SNRI) used primarily to treat depression, anxiety disorders, and neuropathic pain. It is marketed under the brand name Cymbalta.
Chemical Properties	– Molecular Formula: C₁₈H₂₀ClNOS<br>- Molecular Weight: 333.9 g/mol<br>- Appearance: White to off-white powder.
Mechanism of Action	Duloxetine hydrochloride increases the levels of serotonin and norepinephrine in the brain by inhibiting their reuptake, thereby improving mood and reducing pain.
Medical Uses	– Depression: Used to treat major depressive disorder.<br>- Anxiety Disorders: Effective for generalized anxiety disorder and social anxiety disorder.<br>- Neuropathic Pain: Used to treat diabetic peripheral neuropathic pain and fibromyalgia.
Dosage Forms	– Capsules: Available in various strengths for oral administration.<br>- Delayed-Release Tablets: For extended release and better absorption.
Storage Conditions	Store at room temperature (15°C to 30°C), protect from moisture and light.
Safety Information	– Toxicity: Moderate toxicity by ingestion.<br>- Handling: Avoid contact with eyes and skin; wear appropriate protective equipment.<br>- Contraindications: Avoid in patients with uncontrolled narrow-angle glaucoma.
Regulatory Status	– USP: Complies with USP standards.<br>- EP: European Pharmacopoeia reference standard.