Dithiothreitol CAS No.:3483-12-3

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Category:Biochemical Materials   Own Brand:MT  /MOQ:100KG  /From China/  B2B only.

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Introduction

DITHIOTHREITOL (DTT)

CAS No.: 3483-12-3
Molecular Formula: C₄H₁₀O₂S₂
Molecular Weight: 154.25 g/mol


1. BASIC PROPERTIES

Parameter Specification
Appearance White crystalline powder
Purity ≥99.0%
Melting Point 41-44°C (lit.)
Boiling Point 125°C
Density (20°C) 1.04 g/mL
Flash Point >230°F (>110°C)

2. APPLICATIONS

  • Biochemistry:
    • Reduction of protein disulfide bonds (SDS-PAGE sample prep)
    • Cleavage of polyacrylamide gel cross-linkers (bis(acryloyl)cystamine)
  • Neuroscience:
    • Prevention of peptide oxidation (cholecystokinin extraction)
  • Analytical Chemistry:
    • Disulfide bond analysis in protein sequencing

3. PACKAGING & STORAGE

Form Specification
Packaging 25 kg/cardboard drum
Storage – Dry, inert atmosphere
Special Notes – Hygroscopic
– Argon blanket recommended for long-term storage

4. SAFETY & HANDLING

  • GHS Classification:
    • H315+H319: Causes skin/eye irritation
    • H335: May cause respiratory irritation
  • Precautions:
    • Handle under nitrogen/vacuum for sensitive applications
    • Use desiccated containers

5. REGULATORY COMPLIANCE

  • SDS: Available upon request
  • Transport: Non-hazardous (standard conditions)

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